RenalGuard® Articles

This presentation reviews the history of the clinical development of RenalGuard Therapy and the latest clinical data. Please contact Andrew Halpert at ahalpert at to request permission to use these slides.

The following papers and abstracts have been reported on RenalGuard Therapy as a method for reducing the incidence of contrast-induced nephropathy(CIN).

Author Title Source Detail
Luckraz, Heyman The use of the RenalGuard system in cardiac surgery with cardiopulmonary bypass: a first in man prospective, observational, feasibility pilot study openheart 10 October 2017; Volume 2, Issue 4
Prasad, Anand Use of the RenalGuard system to prevent contrast-induced AKI: A meta-analysis Journal of Interventional Cardiology 4 Sept. 2017; 10.1111/joic.12417
Bartorelli, Antonio L, Marenzi, Giancarlo High Urine Output With Matched Hydration for CI-AKI Prevention “Salus Per Aquam” (Health Through Water) JACC: Cardiovascular Interventions Volume 10, Issue 4, February 2017; 364-366
Putzu et al. Prevention of Contrast-Induced Acute Kidney Injury by Furosemide With Matched Hydration in Patients Undergoing Interventional Procedures JACC: Cardiovascular Interventions Volume 10, Issue 4, February 2017; 355-363
Banai, Shmuel Prevention of post procedural acute kidney injury in the catheterization laboratory in a real-world population International Journal of Cardiology 226 (2017) 42–47
Visconti, Gabriella RenalGuard System for the prevention of acute kidney injury in patients undergoing transcatheter aortic valve implantation EuroIntervention 2016;11:e1658-e1661
Briguori, Carlo RenalGuard system in high-risk patients for contrast-induced Acute Kidney Injury American Heart Journal 173; March 2016; 67-76
Barbanti et al. Acute Kidney Injury With the RenalGuard System in Patients Undergoing Transcatheter Aortic Valve Replacement JACC Cardiovascular Interventions 2015;8(12):1595-1604.
T. Usmiani AKIGUARD (acute kidney injury guarding device) independent, randomized and controlled trial on contrast-induced acute kidney injury prevention in the cath lab: in-hospital and one year outcomes European Heart Journal ( 2014 ) 35 ( Abstract Supplement ), 142
Marenzi, Giancarlo, Bartorelli, Antonio, et al. Prevention of Contrast Nephropathy by Furosemide with Matched Hydration: The MYTHOS Trial JACC: Cardiovascular Interventions Volume 5, Issue 1, January 2012, Pages 90-97
Halpert, Andrew RenalGuard - an old idea with a modern twist: preventing contrast-induced nephropathy through induced diuresis with matched replacement EuroPCR 2012 Cardiovascular Innovation Pipeline Poster Session
Bertelli, Luca, et al. Comparison Of Renalguard System, Continuous Venovenous Hemofiltration And Hydration In High-Risk Patients For Contrast-Induced Nephropathy Journal of the American College of Cardiology Volume 59, Issue 13 Suppl S, March 27, 2012
Briguori, Carlo, et al. Renal Insufficiency After Contrast Media Administration Trial II (REMEDIAL II) Circulation Aug 2011; Online ISSN: 1524-4359
Dorval, Jean-Frarncois, et al. Feasibility study of the RenalGuard™ balanced hydration system: A novel strategy for the prevention of contrast-induced nephropathy in high risk patients International Journal of Cardiology Int J Cardiol (2011), 10.1016/j.ijcard.2011.11.035 December 29, 2011