CIN Journal Articles

A number of published papers have explored the risk factors and therapies for CIN, including Matched Fluid Replacement Therapy, the basis of RenalGuard Therapy®. 

Author Title Journal Volume/Page
Bartorelli, Antonio L, Marenzi, Giancarlo High Urine Output With Matched Hydration for CI-AKI Prevention “Salus Per Aquam” (Health Through Water) JACC: Cardiovascular Interventions Volume 10, Issue 4, February 2017; 364-366
Putzu et al. Prevention of Contrast-Induced Acute Kidney Injury by Furosemide With Matched Hydration in Patients Undergoing Interventional Procedures JACC: Cardiovascular Interventions Volume 10, Issue 4, February 2017; 355-363
Brown, JR; Solomon, Richard Chronic Kidney Disease Progression and Cardiovascular Outcomes Following Cardiac Catheterization-A Population-Controlled Study Journal of the American Heart Association 2016 Oct 14;5(10). pii: e003812
Banai, Shmuel Prevention of post procedural acute kidney injury in the catheterization laboratory in a real-world population International Journal of Cardiology 226 (2017) 42–47
Visconti, Gabriella RenalGuard System for the prevention of acute kidney injury in patients undergoing transcatheter aortic valve implantation EuroIntervention 2016;11:e1658-e1661
Nikolsky, Eugenia Thinking kidneys: the prognostic importance of renal function in patients undergoing structural cardiac interventions EuroIntervention 2016: 11:e1571-e1573
Briguori, Carlo RenalGuard system in high-risk patients for contrast-induced acute kidney injury American Heart Journal 173; March 2016; 67-76
Solomon, Richard Improving Intravenous Fluid Therapy for Prevention of Contrast-Induced Nephropathy JACC: Journal of Cardiovascular Interventions J Am Coll Cardiol Intv. 2016;9(1):97-99. doi:10.1016/j.jcin.2015.10.014
Scherner, Maximilian Acute kidney injury after transcatheter aortic valve implantation Journal of Thoracic Disease J Thorac Dis 2015;7(9):1527-1535
Barbanti et al. Acute Kidney Injury With the RenalGuard System in Patients Undergoing Transcatheter Aortic Valve Replacement JACC Cardiovascular Interventions 2015;8(12):1595-1604.
T. Usmiani AKIGUARD (acute kidney injury guarding device) independent, randomized and controlled trial on contrast-induced acute kidney injury prevention in the cath lab: in-hospital and one year outcomes European Heart Journal ( 2014 ) 35 ( Abstract Supplement ), 142
Marenzi, Giancarlo Prevention of Contrast Nephropathy by Furosemide with Matched Hydration: The MYTHOS Trial JACC: Cardiovascular Interventions Volume 5, Issue 1, January 2012, Pages 90-97
Seeliger, Erdmann Contrast-induced kidney injury: mechansims, risk factors, and prevention European Heart Journal January 19, 2012 10.1093/eurheart/ehr494
Dorval, Jean-Francois Feasibility study of the RenalGuard™ balanced hydration system: A novel strategy for the prevention of contrast-induced nephropathy in high risk patients International Journal of Cardiology Int J Cardiol (2011), 10.1016/j.ijcard.2011.11.035 December 29, 2011
Briguori, Carlo Renal Insufficiency After Contrast Media Administration Trial II (REMEDIAL II) Circulation Aug 2011; Online ISSN: 1524-4539
O'Riordan, Michael ACT: No Benefit of N-Acetylcysteine to reduce contrast-induced nephropathy TheHeart.org November 15, 2010
Solomon, Richard J. Contrast-Induced Nephropathy and Long-Term Adverse Events: Cause and Effect Clinical Journal of the American Society of Nephrology Jun 25, 2009; Clin J Am Soc Nephrol 4: 1162-1169, 2009
Brar, Somjot S. Sodium Bicarbonate vs. Sodium Chloride for the Prevention of Contrast Medium-Induced Nephropathy in Patients Undergoing Coronary Angiography - A Randomized Trial Journal of the American Medical Association Sept. 3, 2008; 300(9):1038-1046
Romano, Giulia Contrast Agents and Renal Cell Apoptosis European Heart Journal May 8, 2008; 29(20):2569-2576; doi:10.1093
Solomon, Richard J. Cardiac Angiography in Renally Impaired Patients (CARE) Study. A Randomized Double-Blind Trial of Contrast-Induced Nephropathy in Patients With Chronic Kidney Disease Circulation Jun 2007; 115: 3189 - 3196
Brigouri, Carlo Renal Insufficiency Following Contrast Media Administration Trial (REMEDIAL). A Randomized Comparison of 3 Preventive Strategies Circulation Mar 2007; 115: 1211 - 1217
Marenzi, Giancarlo Comparison of Two Hemofiltration Protocols for Prevention of Contrast-Induced Nephropathy in High-risk Patients American Journal of Medicine 2006; 199; 155-162
Jo, Sang-Ho Renal Toxicity Evaluation and Comparison Between Visipaque (Iodixanol) and Hexabrix (Ioxaglate) in Patients with Renal Insufficiency Undergoing Coronary Angiography. The RECOVER Study: A Randomized Controlled Trial Journal of the American College of Cardiology 2006, Vol. 48, No. 5
Merten, Gregory J. Prevention of Contrast-Induced Nephropathy With Sodium Bicarbonate. A Randomized Controlled Trial Journal of the American Medical Association May 19, 2004; 291;19
Stone, Gregg W. Fenoldopam Mesylate for the Prevention of Contrast-Induced Nephropathy. A Randomized Controlled Trial Journal of the American Medical Association November 5, 2003; 290; 17
Marenzi, Giancarlo The Prevention of Radiocontrast-Agent-Induced nephropathy by Hemofiltration New England Journal of Medicine October 2, 2003; 349;14; 1333-40
Aspelin, Peter Nephrotoxic Effects in High-Risk Patients Undergoing Angiography New England Journal of Medicine February 6, 2003; 348;:491-9
Stevens, Melissa A. A Prospective Randomized Trial of Prevention Measures in Patients at High Risk for Contrast Nephropathy. Results of the P.R.I.N.C.E Study Journal of the American College of Cardiology 1999, Vol. 33, No. 2